Erratum to: Cisplatin-induced epigenetic activation of miR-34a sensitizes bladder cancer cells to chemotherapy
نویسندگان
چکیده
* Correspondence: [email protected]; [email protected] Equal contributors Translational Medicin Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Full list of author information is available at the end of the article
منابع مشابه
Cytotoxicity and Apoptotic Effect of Nanoliposomes loaded with curcumin and miR-34a on MCF-7 and HT29 Cell Lines
Background and aims Colorectal and breast cancers are among the most important causes of mortality in the world. In spite of several attempts, their treatment is yet faced with several problems. Therefore, identification of novel therapeutic approaches is needed. Anti-cancer effects of curcumin and miR-34a have been proposed in various studies. Regarding their pro-apoptotic effects in cancer c...
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Recent studies have established miR-34a as a key effector of the p53 signaling pathway and have implicated its role in multiple cancer types. Here, we establish that miR-34a induces apoptosis, G2 arrest, and senescence in medulloblastoma and renders these cells more sensitive to chemotherapeutic agents. These effects are mediated in part by the direct post-transcriptional repression of the onco...
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Background: A growing body of literature has revealed the effective role of miR-34a, as a tumor suppressor and regulator of expression of multiple targets in tumorigenesis and cancer progression. This study aimed at evaluating the potential effects of miR-34a alone or in combination with paclitaxel on breast cancer cells. Methods: After miR-34a transduction by lentiviral vectors in two MCF-7 an...
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Increased miR-222 levels are associated with a poor prognosis in patients with bladder cancer. However, the role of miR-222 remains unclear. In the present study, we found that miR-222 enhanced the proliferation of both the T24 and the 5637 bladder cancer cell lines. Overexpression of miR-222 attenuated cisplatin-induced cell death in bladder cancer cells. miR-222 activated the Akt/mTOR pathway...
متن کاملExpression and role of miR-34a in bladder cancer.
To investigate the biological function of microRNA-34a (miR-34a) in bladder cancer, the expression of miR-34a was determined using quantitative real-time polymerase chain (qRT-PCR) reaction in 42 cases of bladder cancer. The relationship between the expression of miR-34a and development of bladder cancer was also studied. The mature mimics of miR-34a were chemically synthesized and transiently ...
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